Maruti Nandan Entertainment's Hum Hain Wonder Boys is a tale about a group of five friends viz., Som (Sunil Tripathi), Mangal (Rahul Dayma), Budh (Bablu Jaunpuri), Ravi (Raj Chauhan) and Poornima ((Harshita). Their dream of doing something good for the nation remains unfulfilled when their car meets with an accident which leaves them all dead.
Because of their unfulfilled dream, their souls are just not at peace. That's when they decide to enter the bodies of five orphaned children and fulfil their dream through them. The orphans then realise that they have more powers and capabilities than the children of their age.
What happens when the five dead friends enter the bodies of the orphans and do they become successful in fulfilling their dreams is what forms the rest of the story.