Breed Cinema, Indra Films International and Mehaan Films' Miss Teacher is a story about sex hungry college teacher who happens to prey on her students to satisfy her body thirst. Tanvesh (Rahul Sharma) and Seher (Resham Thakkar), besides loving each other, happen to study in the same class. A hot and sexy new teacher Rose (Komalika Chanda) tries to create a rift between the lovebirds when she starts getting physical with Tanvesh.
On investigation, it gets revealed that, Rose used to be a simple housewife, who got dragged into the world of sleaze and sex by her own husband Amit (Adi Irani). She finds comfort level with Tanvesh and will not allow him to leave her.
What happens next is what forms the rest of the story.