Housefull is a comedy that revolves around the life of unlucky Aarush whose only dream is to find his true love who will be the lucky charm of his life.
Aarush who is considered as a bad omen by his friends and colleagues plans to restart his life with his best friend Bob. Bob lives in England with his wife Hetal who is separated from her family after her marriage with him. Despite Aarush's surprise visit turning out to be a disaster, Hetal accepts him and gets him married to her boss's daughter Devika. But owing to Aarush's unfortunate luck, he is separated from his wife on their first night after she confesses her love for someone else and Aarush meets Sandy and falls for her. Sandy, Aarush, Bob and Hetal get caught in a web of lies as they plan to invite their family to meet their respective partners and Aarush's haunting past resurfaces as he plans to get married to Sandy.